國泰航空 Cathay Pacific 將於 2021 年 2 月 20 日開始削減飛往除悉尼外的所有澳洲航班，以及北美和歐洲航線以回應香港政府最新的防疫要求。即所有返程的機組人員必須接受 14 天的酒店檢疫。以下為被削減的航班：
- Australia – Melbourne, Brisbane, Perth
- New Zealand – Auckland
- United States – San Francisco
- Canada – Vancouver
- Israel – Tel Aviv (one flight will operate from Hong Kong on 23rd February)
- South Korea – Seoul
- Vietnam – Ho Chi Minh City
- Malaysia – Kuala Lumpur
- Philippines – Cebu (one return flight will operate on 26th February)
- Taiwan – Kaohsiung (one return flight will operate on 27th February)
根據早前報導，為了應對這次政府的新政策，國泰將會安排有關的機組人員分別入住國泰城，及於 9 March 2021 起入住位於在太古城旁，同屬太古集團旗下的 EAST Hong Kong 酒店以作隔離之用。
至於以下的航班將會保持營運：
- Australia – Sydney
- United States – Los Angeles, New York
- Canada – Toronto
- United Kingdom – London (one-way from Hong Kong only)
- Netherlands – Amsterdam (one-way from Amsterdam only)
- Indonesia – Jakarta, Surabaya
- Japan – Tokyo, Osaka
- Singapore – Singapore
- Philippines – Manila
- Thailand – Bangkok
- Taiwan – Taipei
- China – Beijing, Shanghai
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